Search Result

Results for "

Protein kinase C

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (2) ADC Cytotoxin (1) Akt (2) Antibiotic (7) Apoptosis (25) Autophagy (7) Bacterial (4) Bcl-2 Family (1) Bcr-Abl (2) Biochemical Assay Reagents (2) c-Kit (8) c-Met/HGFR (5) Calcium Channel (2) Casein Kinase (1) CDK (3) CMV (1) COX (1) Cytochrome P450 (2) Dopamine β-hydroxylase (2) Drug Metabolite (3) E1/E2/E3 Enzyme (1) EGFR (2) Endogenous Metabolite (6) Estrogen Receptor/ERR (2) FGFR (2) FLT3 (3) Fluorescent Dye (1) Fungal (1) HIV (1) HSP (1) Influenza Virus (4) Insulin Receptor (1) Isotope-Labeled Compounds (2) JAK (1) JNK (1) Monoamine Oxidase (2) Myosin (3) NF-κB (1) NO Synthase (1) Nucleoside Antimetabolite/Analog (1) Orthopoxvirus (3) PDGFR (6) PDK-1 (1) Phosphatase (2) Phosphodiesterase (PDE) (1) PI3K (1) PKA (8) PKC (88) PKD (1) Polo-like Kinase (PLK) (1) PPAR (1) RAD51 (2) Raf (3) Reactive Oxygen Species (1) RET (3) Reverse Transcriptase (3) Ribosomal S6 Kinase (RSK) (1) RIP kinase (1) ROCK (3) SARS-CoV (4) Ser/Thr Protease (2) SphK (1) Src (3) STAT (1) Syk (1) Telomerase (2) Topoisomerase (5) Trk Receptor (1) VEGFR (3)
By Research Areas:	Cancer (71) Cardiovascular Disease (4) Endocrinology (2) Infection (17) Inflammation/Immunology (23) Metabolic Disease (8) Neurological Disease (14)
Click Chemistry:	Alkynes (1)

137

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P1401

Protein Kinase C (19-36)	PKC	Metabolic Disease
Protein Kinase C (19-36) is a pseudosubstrate peptide inhibitor of protein kinase C (PKC), with an IC₅₀ of 0.18 μM. Protein Kinase C (19-36) markedly attenuated vascular hyperproliferation and hypertrophy as well as glucose-induced suppression of natriuretic peptide receptor response .

HY-P1746

Protein Kinase C (19-31) 1 Publications Verification PKC (19-31)	PKC	Inflammation/Immunology
Protein Kinase C (19-31), a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31), is used as protein kinase C substrate peptide for testing the protein kinase C activity .

HY-P3764

Protein kinase C substrate	PKC	Others
Protein kinase C substrate is a substrate of Protein kinase C, can be used to detect protein. Protein kinase C is a key regulatory element in signal transduction and exerts its effects by catalysing specific substrate phosphorylation .

HY-P3841

Protein Kinase C (beta) Peptide	PKC	Others
Protein Kinase C β Peptide is a peptide fragment of Protein Kinase Cβ. Protein Kinase Cβ is related with hyperglycemia decreases endothelium-derived nitric oxide. Inhibition of Protein kinase Cβ prevents the reduction in endothelium-dependent vasodilation induced by acute hyperglycemia .

HY-P3838

Protein Kinase C (gamma) Peptide	PKC	Others
Protein Kinase C γ Peptide is a peptide fragment of Protein Kinase Cγ. Protein Kinase Cγ is a protein causative for dominant ataxia, that can negatively regulate nuclear import of recessive-ataxia-related aprataxin .

HY-P3842

Protein Kinase C (661-671)	PKC	Cancer
Protein Kinase C (661-671) is a fragment peptide of β1 subspecies of protein kinase C (PKC). PKC plays a role in cellular growth control and tumor promotion .

HY-P1288

Protein Kinase C (530-558) PKC fragment (530-558)	PKC	Others
Protein Kinase C (530-558), a peptide fragment of protein kinase C (PKC), is a potent PKC activator. Protein Kinase C (530-558) significantly inhibits osteoclastic bone resorption .

HY-P3892

Protein Kinase C (19-35) Peptide	PKC	Inflammation/Immunology
Protein Kinase C (19-35) Peptide is the PKC pseudosubstrate inhibitor/region. Protein Kinase C (19-35) Peptide possibly blocks the substrate-binding site in its kinase domain, makes the cytoplasmic form of PKC inactive .

HY-P1746A

Protein Kinase C (19-31) (TFA) PKC (19-31) (TFA)	PKC	Inflammation/Immunology
Protein Kinase C (19-31) TFA, a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31), is used as protein kinase C substrate peptide for testing the protein kinase C activity .

HY-P3766

Protein kinase C (alpha) peptide TFA	PKC	Others
Protein kinase C α peptide (TFA) is a peptide of PKC-α. PKC-α acts as a lipid-dependent ser/thr protein kinase, can modulate various cellular processes, including cell survival, proliferation, differentiation, migration, adhesion and so on .

HY-P3879

Protein Kinase C (660-673)

PKC βII (660-673)
PKC Others

Protein Kinase C (660-673) (PKC βII (660-673)) is the PKC βII V5 peptide with RACK1-binding affinity .

Protein Kinase C (660-673) PKC βII (660-673)	PKC	Others
Protein Kinase C (660-673) (PKC βII (660-673)) is the PKC βII V5 peptide with RACK1-binding affinity .

HY-108136A

Bisindolylmaleimide X hydrochloride 2 Publications Verification BIM-X hydrochloride; Ro31-8425 hydrochloride	PKC CDK	Cardiovascular Disease
Bisindolylmaleimide X hydrochloride (BIM-X hydrochloride) is a potent and selective protein kinase C (PKC) inhibitor. Bisindolylmaleimide X hydrochloride is a potent *cyclin-dependent kinase* 2 (CDK2) antagonist with an IC₅₀** of 200 nM .

HY-105416

Calphostin C UCN-1028C	Antibiotic PKC Apoptosis	Infection Cancer
Calphostin C is a potent and specific inhibitor of protein kinase C. Calphostin C is an antitumor antibiotic. Calphostin C has 1000 times more inhibitory to protein kinase C with an IC₅₀ of 0.05 μM than other protein kinases. Calphostin C induces apoptosis in some tumor cell lines. Calphostin C has potent cytotoxic activity and antitumor activity .

HY-P1289A

[Ala107]MBP(104-118)

PKC Others

[Ala107]MBP(104-118) is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC₅₀s ranging from 46-145 μM .
HY-P1289

[Ala113]MBP(104-118)

PKC Others

[Ala113]MBP(104-118) is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC₅₀s ranging from 28-62 μM .
HY-P1289C

[Ala113]MBP(104-118) TFA

PKC Others

[Ala113]MBP(104-118) TFA is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC₅₀s ranging from 28-62 μM .
HY-P1289B

[Ala107]MBP(104-118) TFA

PKC Others

[Ala107]MBP(104-118) TFA is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC₅₀s ranging from 46-145 μM .

[Ala107]MBP(104-118)	PKC	Others
[Ala107]MBP(104-118) is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC₅₀s ranging from 46-145 μM .

[Ala113]MBP(104-118)	PKC	Others
[Ala113]MBP(104-118) is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC₅₀s ranging from 28-62 μM .

[Ala113]MBP(104-118) TFA	PKC	Others
[Ala113]MBP(104-118) TFA is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC₅₀s ranging from 28-62 μM .

[Ala107]MBP(104-118) TFA	PKC	Others
[Ala107]MBP(104-118) TFA is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC₅₀s ranging from 46-145 μM .

HY-P1088

*[Ser25] Protein* Kinase C (19-31)**	PKC	Others
[Ser25] Protein Kinase C (19-31) is a substrate of protein kinase C (PKC) (K_m: 0.3 μM). [Ser25] Protein Kinase C (19-31) is derived from the pseudo-substrate regulatory domain of PKCα (19-31) with a Serine at position 25 replacing the wild-type Alanine .

HY-P2673

Lys-Arg-Thr-Leu-Arg-Arg KRTLRR	EGFR	Others
Lys-Arg-Thr-Leu-Arg-Arg (KRTLRR) is a hexapeptide. Lys-Arg-Thr-Leu-Arg-Arg is a substrate of protein kinase C from EGF receptor. Lys-Arg-Thr-Leu-Arg-Arg can be used to determine the activity of protein kinase C .

HY-P3784

FKKSFKL-NH2	PKC	Metabolic Disease Inflammation/Immunology Cancer
FKKSFKL-NH2 is a protein kinase C-selective peptide. FKKSFKL-NH2 can be used for the research of various biochemical .

HY-108602

Bryostatin 3	PKC	Cancer
Bryostatin 3, a macrocyclic lactone, is a protein kinase C activator, with a K_i of 2.75 nM. Bryostatin 3 can block 12-O-tetradecanoylphorbol-13-acetate (TPA) inhibition of cell proliferation, yet did not block TPA-enhanced cell-substratum adhesion .

HY-P5886

PKC 20-28,myristoylated Myristoylated Protein kinase C inhibitor 20-28	PKC	Cancer
PKC 20-28,myristoylated (Myristoylated protein kinase C inhibitor 20-28) is a cell-permeable PKC inhibitor that can be used in cancer research .

HY-129624A

Bisindolylmaleimide VIII acetate Ro 31-7549 acetate; Bis VIII acetate	PKC Apoptosis	Inflammation/Immunology Cancer
Bisindolylmaleimide VIII acetate (Ro 31-7549 acetate) is a potent and selective protein kinase C (PKC) inhibitor with an IC₅₀ of 158 nM for rat brain PKC. Bisindolylmaleimide VIII acetate has IC₅₀s of 53, 195, 163, 213, and 175 nM for PKC-α, PKC-β_I, PKC-β_II, PKC-γ, PKC-ε, respectively . Bisindolylmaleimide VIII acetate facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases .

HY-N0453

Hypericin 2 Publications Verification	Apoptosis Influenza Virus Antibiotic Monoamine Oxidase PKC Cytochrome P450 Dopamine β-hydroxylase Reverse Transcriptase Telomerase	Infection Neurological Disease Cancer
Hypericin is a naturally occurring substance found in Hyperlcurn perforatum L. Hypericin is an inhibitor of PKC (protein kinase C), MAO (monoaminoxidase), dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP (cytochrome P450). Hypericin shows antitumor, antiviral, antidepressive activities, and can induce apoptosis .

HY-131900

Protein kinase inhibitor H-7	PKC	Cancer
Protein kinase inhibitor H-7 is a potent inhibitor of protein kinase C (PKC) and cyclic nucleotide dependent protein kinase, with a K_i of 6 μM for PKC .

HY-148794

Risvodetinib IkT-148009	c-Met/HGFR	Cancer
Risvodetinib is a potent **protein tyrosine kinase** inhibitor. Risvodetinib involves in synthesis of Abelson protein kinases (c-Abl1, c-Abl2, and c-kit) inhibitor .

HY-100983

Protein kinase inhibitor H-7 dihydrochloride	PKC	Cancer
Protein kinase inhibitor H-7 dihydrochloride is a potent PKC (protein kinase C) inhibitor. At 100 μM, Protein kinase inhibitor H-7 dihydrochloride completely inhibits both TPA (skin tumour promoter, 12-O-tetradecanoylphorbol-13-acetate) and phospholipase C-induced ODC (ornithine decarboxylase) .

HY-100984

HA-100 1 Publications Verification	PKA PKC Myosin ROCK	Cancer
HA-100 is a potent **protein kinase inhibitor, with IC₅₀s of 4 μM, 8 μM, 12 μM and 240 μM for cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA)*, protein* kinase C (PKC) and *MLC-kinase, respectively. HA-100 also used as a ROCK* inhibitor .

HY-100984A

HA-100 hydrochloride	PKA PKC Myosin ROCK	Cancer
HA-100 hydrochloride is a potent **protein kinase inhibitor, with IC₅₀*s of 4 μM, 8 μM, 12 μM and 240 μM for cGMP-dependent protein* kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and *MLC-kinase, respectively. HA-100 hydrochloride also used as a ROCK* inhibitor .

HY-12880

HA-100 dihydrochloride	Myosin PKA PKC ROCK	Cancer
HA-100 dihydrochloride is a potent **protein kinase inhibitor, with IC₅₀*s of 4 μM, 8 μM, 12 μM and 240 μM for cGMP-dependent protein* kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and *MLC-kinase, respectively. HA-100 dihydrochloride also used as a ROCK* inhibitor .

HY-117393

Bisindolylmaleimide III	PKC	Cancer
Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC). Bisindolylmaleimide III selectively interacts with either PKCα or ribosomal S6 protein kinase 1 after activation of these kinases .

HY-10183

Go6976

4 Publications Verification

PKC Influenza Virus Cancer

Go6976 is a Protein Kinase C (PKC) inhibitor, with an IC₅₀ of 20 nM.
HY-112384

Safingol

L-threo-dihydrosphingosine
PKC Cancer

Safingol is a lyso-sphingolipid PKC (protein kinase C ) inhibitor .
HY-N11003

Vanicoside A

PKC Others

Vanicoside A is a protein kinase C(PKC) inhibitor from Polygonum pensylvanicum .

Go6976 4 Publications Verification	PKC Influenza Virus	Cancer
Go6976 is a Protein Kinase C (PKC) inhibitor, with an IC₅₀ of 20 nM.

Safingol L-threo-dihydrosphingosine	PKC	Cancer
Safingol is a lyso-sphingolipid PKC (protein kinase C ) inhibitor .

Vanicoside A	PKC	Others
Vanicoside A is a protein kinase C(PKC) inhibitor from Polygonum pensylvanicum .

HY-101962

HNMPA	Insulin Receptor	Metabolic Disease
HNMPA is a membrane impermeable insulin receptor tyrosine kinase inhibitor. HNMPA inhibits serine and tyrosine autophosphorylation by the human insulin receptor. HNMPA has no effect on protein kinase C or cyclic AMP-dependent protein kinase activities

HY-P1821

Myelin Basic Protein MHP4-14	PKC	Neurological Disease
Myelin Basic Protein (MHP4-14), a synthetic peptide comprising residues 4-14 of myelin basic protein, is a very selective PKC substrate (K_m=7 μM). Myelin Basic Protein is not phosphorylated by cyclic AMP-dependent protein kinase, casein kinases I and II, Ca ²⁺/calmodulin-dependent protein kinase II, or phosphorylase kinase, and can be routinely used for the assay of protein kinase C with low background in the crude tissue extracts .

HY-P1821A

Myelin Basic Protein TFA 1 Publications Verification MHP4-14 TFA	PKC	Neurological Disease
Myelin Basic Protein (MHP4-14) TFA, a synthetic peptide comprising residues 4-14 of myelin basic protein, is a very selective PKC substrate (K_m=7 μM). Myelin Basic Protein TFA is not phosphorylated by cyclic AMP-dependent protein kinase, casein kinases I and II, Ca ²⁺/calmodulin-dependent protein kinase II, or phosphorylase kinase, and can be routinely used for the assay of protein kinase C with low background in the crude tissue extracts .

HY-12359

TPPB

1 Publications Verification

PKC Neurological Disease

TPPB is a cell-permeable benzolactam-derived protein kinase C (PKC) activator with a K_i of 11.9 nM.

TPPB 1 Publications Verification	PKC	Neurological Disease
TPPB is a cell-permeable benzolactam-derived protein kinase C (PKC) activator with a K_i of 11.9 nM.

HY-P3741

[Ala9,10, Lys11,12] Glycogen Synthase (1-12)	PKC	Neurological Disease
[Ala9,10, Lys11,12] Glycogen Synthase (1-12) is a selective substrate for phosphorylation by protein kinase C (PKC). [Ala9,10, Lys11,12] Glycogen Synthase (1-12) can be used to determine the activity of protein kinase C .

HY-D1751

RIM-1

Fluorescent Dye PKC Others

RIM-1 is a fluorescent probe for protein kinase C (PKC) that can be used to visualize the distribution of PKC in cells.
HY-133083

BAY-474

c-Met/HGFR Cancer

BAY-474 is a tyrosine-protein kinase c-Met inhibitor. BAY-474 acts as an epigenetics probe .

RIM-1	Fluorescent Dye PKC	Others
RIM-1 is a fluorescent probe for protein kinase C (PKC) that can be used to visualize the distribution of PKC in cells.

BAY-474	c-Met/HGFR	Cancer
BAY-474 is a tyrosine-protein kinase *c-Met* inhibitor. BAY-474 acts as an epigenetics probe .

HY-101047

D-erythro-Sphingosine 2 Publications Verification Erythrosphingosine; erythro-C18-Sphingosine; trans-4-Sphingenine
D-erythro-Sphingosine (Erythrosphingosine) is a very potent activator of *p32-kinase* with an EC₅₀ of 8 μM, and inhibits protein kinase C (PKC). D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator .

HY-123979

ζ-Stat NSC37044	PKC Apoptosis	Cancer
ζ-Stat (NSC37044) is a specific and atypical PKC-ζ inhibitor, with an IC₅₀ of 5 μM. ζ-Stat can reduce melanoma cell lines proliferation and induce apoptosis, and has antitumor activity in vitro .

HY-123979A

ζ-Stat trisodium NSC37044 trisodium	PKC Apoptosis	Cancer
ζ-Stat trisodium (NSC37044 trisodium) is a specific and atypical PKC-ζ inhibitor, with an IC₅₀ of 5 μM. ζ-Stat trisodium can reduce melanoma cell lines proliferation and induce apoptosis, and has antitumor activity in vitro .

HY-130516

Cdc7-IN-4	CDK	Cancer
Cdc7-IN-4 (compound I-C) is a potent Cdc7 kinase inhibitor extracted from patent WO2019165473A1, compound I-C. Cdc7 is a serine-threonine protein kinase enzyme which is essential for the initiation of DNA replication in the cell cycle .

HY-13977A

PKR-IN-C16 2 Publications Verification	Apoptosis	Neurological Disease
PKR-IN-C16 (Compound C16) is a specific double-stranded RNA-dependent protein kinase (PKR) inhibitor. PKR-IN-C16 shows promising neuroprotective properties and can rescue acute brain lesions .

HY-112782

VTX-27

PKC Inflammation/Immunology

VTX-27 is a selective protein kinase C θ (PKC θ) inhibitor, with K_is of 0.08 nM and 16 nM for PKC θ and PKC δ.
HY-126146

PKC-iota inhibitor 1

2 Publications Verification

PKC Cancer

PKC-iota inhibitor 1 (compound 19) is a protein kinase C-iota (PKC-ι ℩) inhibitor with an IC₅₀ value of 0.34 μM .

HY-P3940

Ac-MBP (4-14) Peptide	PKC	Others
Ac-MBP (4-14) Peptide is an acetylated MBP (4-14) peptide. MBP (4-14) Peptide is a very selective (protein kinase C) PKC substrate. Ac-MBP (4-14) Peptide can be used for PKC assay in extracts without prior purification to eliminate interfering protein kinases or phosphatases .

HY-13343

ZM 336372 1 Publications Verification	Raf Apoptosis	Cancer
ZM 336372 is a potent inhibitor of the protein kinase *c-Raf. The IC₅₀* value is 0.07 μM in the standard assay, which contains 0.1 mM ATP.

Cat. No.	Product Name

HY-L016

Protein Tyrosine Kinase Compound Library

1055 compounds

Protein tyrosine kinases (PTKs) are key signaling molecules and important drug targets. Two classes of PTKs are present in cells: the transmembrane receptor PTKs (RTKs) and the nonreceptor PTKs. The RTK family includes the receptors for insulin and for many growth factors, such as EGFR, FGFR, PDGFR, VEGFR, and NGFR. RTKs are transmembrane glycoproteins that are activated by the binding of their ligands, and they transduce the extracellular signal to the cytoplasm by phosphorylating tyrosine residues on the receptors themselves (autophosphorylation) and on downstream signaling proteins. Their principal functions of PTKs involve the regulation of multicellular aspects of the organism. Cell to cell signals concerning growth, differentiation, adhesion, motility, and death are frequently transmitted through tyrosine kinases. In humans, tyrosine kinases have been demonstrated to play significant roles in the development of many disease states, including diabetes and cancers.

MCE designs a unique collection of 1055 compounds that act as a useful tool for PTKs-related drug screening and disease research.

HY-L010

MAPK Compound Library

510 compounds

MAPK families play an important role in complex cellular programs like proliferation, differentiation, development, transformation, and apoptosis. In mammalian cells, four MAPK families have been clearly characterized: ERK1/2, C-Jun N-terminal kinse/stress-activated protein kinase (JNK/SAPK) , p38 kinase and ERK5. They respond to different signals. Each MAPK-related cascade consists of three enzymes that are activated in series: a MAPK kinase kinase (MAPKKK), a MAPK kinase (MAPKK) and a MAP kinase (MAPK). MAPK signaling pathways has been implicated in the development of many human diseases including Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS) and various types of cancers.

MCE designs a unique collection of 510 MAPK signaling pathway inhibitors that act as a useful tool for MAPK-related drug screening and disease research.

Cat. No.	Product Name	Target	Research Area

HY-P1401

Protein Kinase C (19-36)	PKC	Metabolic Disease
Protein Kinase C (19-36) is a pseudosubstrate peptide inhibitor of protein kinase C (PKC), with an IC₅₀ of 0.18 μM. Protein Kinase C (19-36) markedly attenuated vascular hyperproliferation and hypertrophy as well as glucose-induced suppression of natriuretic peptide receptor response .

HY-P1746

Protein Kinase C (19-31) 1 Publications Verification PKC (19-31)	PKC	Inflammation/Immunology
Protein Kinase C (19-31), a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31), is used as protein kinase C substrate peptide for testing the protein kinase C activity .

HY-P3764

Protein kinase C substrate	PKC	Others
Protein kinase C substrate is a substrate of Protein kinase C, can be used to detect protein. Protein kinase C is a key regulatory element in signal transduction and exerts its effects by catalysing specific substrate phosphorylation .

HY-P3841

Protein Kinase C (beta) Peptide	PKC	Others
Protein Kinase C β Peptide is a peptide fragment of Protein Kinase Cβ. Protein Kinase Cβ is related with hyperglycemia decreases endothelium-derived nitric oxide. Inhibition of Protein kinase Cβ prevents the reduction in endothelium-dependent vasodilation induced by acute hyperglycemia .

HY-P3838

Protein Kinase C (gamma) Peptide	PKC	Others
Protein Kinase C γ Peptide is a peptide fragment of Protein Kinase Cγ. Protein Kinase Cγ is a protein causative for dominant ataxia, that can negatively regulate nuclear import of recessive-ataxia-related aprataxin .

HY-P3842

Protein Kinase C (661-671)	PKC	Cancer
Protein Kinase C (661-671) is a fragment peptide of β1 subspecies of protein kinase C (PKC). PKC plays a role in cellular growth control and tumor promotion .

HY-P1288

Protein Kinase C (530-558) PKC fragment (530-558)	PKC	Others
Protein Kinase C (530-558), a peptide fragment of protein kinase C (PKC), is a potent PKC activator. Protein Kinase C (530-558) significantly inhibits osteoclastic bone resorption .

HY-P3892

Protein Kinase C (19-35) Peptide	PKC	Inflammation/Immunology
Protein Kinase C (19-35) Peptide is the PKC pseudosubstrate inhibitor/region. Protein Kinase C (19-35) Peptide possibly blocks the substrate-binding site in its kinase domain, makes the cytoplasmic form of PKC inactive .

HY-P1746A

Protein Kinase C (19-31) (TFA) PKC (19-31) (TFA)	PKC	Inflammation/Immunology
Protein Kinase C (19-31) TFA, a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31), is used as protein kinase C substrate peptide for testing the protein kinase C activity .

HY-P1803

Protein Kinase C Peptide Substrate PKCε; PRKCE ; Peptide Epsilon	Peptides	Neurological Disease Inflammation/Immunology Endocrinology
Protein Kinase C Peptide Substrate is targeted to a specific cellular compartment in a manner dependent on second messengers and on specific adapter proteins in response to extracellular signals that activate G-protein-coupled receptors, tyrosine kinase receptors, or tyrosine kinase-coupled receptors. Protein Kinase C Peptide Substrate then regulates various physiological functions including the activation of nervous, endocrine, exocrine, inflammatory, and immune systems .

HY-P3766

Protein kinase C (alpha) peptide TFA	PKC	Others
Protein kinase C α peptide (TFA) is a peptide of PKC-α. PKC-α acts as a lipid-dependent ser/thr protein kinase, can modulate various cellular processes, including cell survival, proliferation, differentiation, migration, adhesion and so on .

HY-P3879

Protein Kinase C (660-673)

PKC βII (660-673)
PKC Others

Protein Kinase C (660-673) (PKC βII (660-673)) is the PKC βII V5 peptide with RACK1-binding affinity .
HY-P1289A

[Ala107]MBP(104-118)

PKC Others

[Ala107]MBP(104-118) is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC₅₀s ranging from 46-145 μM .
HY-P1289

[Ala113]MBP(104-118)

PKC Others

[Ala113]MBP(104-118) is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC₅₀s ranging from 28-62 μM .
HY-P1289C

[Ala113]MBP(104-118) TFA

PKC Others

[Ala113]MBP(104-118) TFA is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC₅₀s ranging from 28-62 μM .
HY-P1289B

[Ala107]MBP(104-118) TFA

PKC Others

[Ala107]MBP(104-118) TFA is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC₅₀s ranging from 46-145 μM .

HY-P1088

*[Ser25] Protein* Kinase C (19-31)**	PKC	Others
[Ser25] Protein Kinase C (19-31) is a substrate of protein kinase C (PKC) (K_m: 0.3 μM). [Ser25] Protein Kinase C (19-31) is derived from the pseudo-substrate regulatory domain of PKCα (19-31) with a Serine at position 25 replacing the wild-type Alanine .

HY-P2673

Lys-Arg-Thr-Leu-Arg-Arg KRTLRR	EGFR	Others
Lys-Arg-Thr-Leu-Arg-Arg (KRTLRR) is a hexapeptide. Lys-Arg-Thr-Leu-Arg-Arg is a substrate of protein kinase C from EGF receptor. Lys-Arg-Thr-Leu-Arg-Arg can be used to determine the activity of protein kinase C .

HY-P3784

FKKSFKL-NH2

PKC Metabolic Disease Inflammation/Immunology Cancer

FKKSFKL-NH2 is a protein kinase C-selective peptide. FKKSFKL-NH2 can be used for the research of various biochemical .

HY-P5886

PKC 20-28,myristoylated Myristoylated Protein kinase C inhibitor 20-28	PKC	Cancer
PKC 20-28,myristoylated (Myristoylated protein kinase C inhibitor 20-28) is a cell-permeable PKC inhibitor that can be used in cancer research .

HY-P1821

Myelin Basic Protein MHP4-14	PKC	Neurological Disease
Myelin Basic Protein (MHP4-14), a synthetic peptide comprising residues 4-14 of myelin basic protein, is a very selective PKC substrate (K_m=7 μM). Myelin Basic Protein is not phosphorylated by cyclic AMP-dependent protein kinase, casein kinases I and II, Ca ²⁺/calmodulin-dependent protein kinase II, or phosphorylase kinase, and can be routinely used for the assay of protein kinase C with low background in the crude tissue extracts .

HY-P1402

[Glu27]-PKC (19-36)	Peptides	Others
[Glu27]-PKC (19-36) is an inactive control for protein kinase C (PKC) (19-36). PKC (19-36) is a pseudosubstrate peptide inhibitor of protein kinase C, it may be responsible for maintaining the enzyme in the inactive form in the absence of allosteric activators such as phospholipids .

HY-P3741

[Ala9,10, Lys11,12] Glycogen Synthase (1-12)	PKC	Neurological Disease
[Ala9,10, Lys11,12] Glycogen Synthase (1-12) is a selective substrate for phosphorylation by protein kinase C (PKC). [Ala9,10, Lys11,12] Glycogen Synthase (1-12) can be used to determine the activity of protein kinase C .

HY-P5466

S6(229-239)	Peptides	Others
S6(229-239) is a biological active peptide. (This is a synthetic peptide substrate for S6 kinase shown to be phosphorylated by protein kinase c with phosphorylation site identified at Ser235)

HY-P3940

Ac-MBP (4-14) Peptide	PKC	Others
Ac-MBP (4-14) Peptide is an acetylated MBP (4-14) peptide. MBP (4-14) Peptide is a very selective (protein kinase C) PKC substrate. Ac-MBP (4-14) Peptide can be used for PKC assay in extracts without prior purification to eliminate interfering protein kinases or phosphatases .

HY-P3815

Casein Kinase 2 Substrate Peptide 1 Publications Verification	Casein Kinase	Others
Casein Kinase 2 Substrate Peptide is a common CK2 substrate peptide. Casein Kinase 2 Substrate Peptide is synthesized with its C-terminus conjugated to 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid (EDANS). Casein Kinase 2 Substrate Peptide can be used for protein kinase CK2 activity determination .

HY-P3743

p60c-src Substrate	Peptides	Others
p60c-src Substrate is an efficient and specific substrate for *p60c-src* protein tyrosine kinase (PTK). p60c-src Substrate can be used to synthesize chimeric branched peptides .

HY-P1834

MARCKS Peptide(151-175), Phosphorylated	Peptides	Inflammation/Immunology
MARCKS Peptide(151-175), Phosphorylated is a phosphorylated peptide corresponding to the basic effector domain of myristoylated alanine-rich protein kinase C substrate protein (MARCKS). Phosphorylation of MARCKS Peptide (151-175) reverses its inhibition of phospholipase C (PLC)-catalyzed hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) .

HY-P1399

Pep2m, myristoylated Myr-Pep2m	PKC	Neurological Disease
Pep2m, myristoylated (Myr-Pep2m) is a cell-permeable peptide. Pep2m, myristoylated can disrupt the protein kinase ζ (PKMζ) downstream targets, N-ethylmaleimide-sensitive factor/glutamate receptor subunit 2 (NSF/GluR2) interactions. PKMζ is an autonomously active isozyme of protein kinase C (PKC) .

HY-P2298

TAT-P4-(DATC5)2	Peptides	Neurological Disease
TAT-P4-(DATC5)2 is a high-affinity peptide inhibitor of the *PICK1 (protein* interacting with C kinase-1) PDZ domain, with a K_i** of 1.7 nM. TAT-P4-(DATC5)2 can inhibit addiction in rats .

HY-P1399A

Pep2m, myristoylated TFA Myr-Pep2m TFA	PKC	Neurological Disease
Pep2m, myristoylated TFA (Myr-Pep2m TFA) is a cell-permeable peptide. Pep2m, myristoylated TFA can disrupt the protein kinase ζ (PKMζ) downstream targets, N-ethylmaleimide-sensitive factor/glutamate receptor subunit 2 (NSF/GluR2) interactions. PKMζ is an autonomously active isozyme of protein kinase C (PKC) .

HY-P2298A

TAT-P4-(DATC5)2 TFA	Peptides	Neurological Disease
TAT-P4-(DATC5)2 TFA is a high-affinity peptide inhibitor of the *PICK1 (protein* interacting with C kinase-1) PDZ domain, with a K_i** of 1.7 nM. TAT-P4-(DATC5)2 TFA can inhibit addiction in rats .

HY-106262

Delcasertib KAI-9803; BMS-875944	PKC	Cardiovascular Disease Inflammation/Immunology
Delcasertib (KAI-9803) is a potent and selective δ-protein kinase C (δPKC) inhibitor. Delcasertib (KAI-9803) could ameliorate injury associated with ischemia and reperfusion in animal models of acute myocardial infarction (MI) .

HY-106262B

Delcasertib hydrochloride 1 Publications Verification KAI-9803 hydrochloride; BMS-875944 hydrochloride	PKC	Cardiovascular Disease Inflammation/Immunology
Delcasertib (KAI-9803) hydrochloride is a potent and selective δ-protein kinase C (δPKC) inhibitor. Delcasertib (KAI-9803) hydrochloride could ameliorate injury associated with ischemia and reperfusion in animal models of acute myocardial infarction (MI) .

HY-P3083

N-Myristoyl-Lys-Arg-Thr-Leu-Arg	PKC	Inflammation/Immunology
N-Myristoyl-Lys-Arg-Thr-Leu-Arg is a protein kinase C (PKC) inhibitor with an IC₅₀ value of 75 μM. N-Myristoyl-Lys-Arg-Thr-Leu-Arg inhibits IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat .

HY-P5452

PKCd (8-17)	Peptides	Others
PKCd (8-17) is a biological active peptide. (This peptide is derived from the V1 domain of protein kinase C (PKC)d. It inhibits phorbol 12-myristate 13-acetate (PMA)-induced PKCd translocation and activation. Inhibition of PKCd reduces ischemia damage in cardiac and cerebral cells, induces proliferation of fibroblasts, and inhibits graft coronary artery disease in mice.)

HY-107024

Osteogenic Growth Peptide (10-14) OGP(10-14); Historphin	Src	Others
Osteogenic Growth Peptide (10-14) (OGP(10-14)), the C-terminal truncated pentapeptide of osteogenic growth peptide (OGP), retains the full OGP-like activity. Osteogenic Growth Peptide (10-14) is responsible for the binding to the OGP receptor and activates an intracellular Gi-protein-MAP kinase signaling pathway. Osteogenic Growth Peptide (10-14) is a potent mitogen and stimulator of osteogenesis and hematopoiesis. Osteogenic Growth Peptide (10-14) acts as a Src inhibitor .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0453

Hypericin 2 Publications Verification	Natural Products Classification of Application Fields Source classification Guttiferae Phenols Polyphenols Hyperlcurn perforatum L. Plants Disease Research Fields Cancer	Apoptosis Influenza Virus Antibiotic Monoamine Oxidase PKC Cytochrome P450 Dopamine β-hydroxylase Reverse Transcriptase Telomerase
Hypericin is a naturally occurring substance found in Hyperlcurn perforatum L. Hypericin is an inhibitor of PKC (protein kinase C), MAO (monoaminoxidase), dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP (cytochrome P450). Hypericin shows antitumor, antiviral, antidepressive activities, and can induce apoptosis .

HY-N4322

Decursinol angelate	Pseudognaphalium affine (D. Don) Anderberg Classification of Application Fields Source classification Coumarins Phenylpropanoids Plants Umbelliferae Inflammation/Immunology Disease Research Fields Cancer	PKC
Decursinol angelate, a cytotoxic and protein kinase C (PKC) activating agent from the root of Angelica gigas, possesses anti-tumor and anti-inflammatory activities .

HY-N11003

Vanicoside A	Structural Classification Polygonaceae Source classification Phenols Polyphenols Plants Persicaria orientalis (L.) Spach	PKC
Vanicoside A is a protein kinase C(PKC) inhibitor from Polygonum pensylvanicum .

HY-N10393

Vibsanin A	Structural Classification Natural Products Classification of Application Fields Viburnaceae Source classification Viburnum awabuki K. Koch Plants Disease Research Fields Cancer	PKC HSP
Vibsanin A, a protein kinase C (PKC) activator, exhibits anti-proliferative activity against human cancer cell lines. Vibsanin A is also a HSP90 inhibitor .

HY-108262

UCN-02 7-epi-Hydroxystaurosporine	Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics Cancer	PKC PKA
UCN-02 (7-epi-Hydroxystaurosporine) is a selective protein kinase C (PKC) inhibitor produced by Streptomyces strain N-12, with IC₅₀s of 62 nM and 250 nM for PKC and protein kinase A (PKA), respectively. UCN-02 (7-epi-Hydroxystaurosporine) displays cytotoxic effect on the growth of HeLa S3 cells .

HY-118384

Sangivamycin 2 Publications Verification NSC 65346; BA-90912	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields Cancer	PKC Nucleoside Antimetabolite/Analog
Sangivamycin (NSC 65346), a nucleoside analog, is a potent inhibitor of protein kinase C (PKC) with an K_i of 10 μM. Sangivamycin has potent antiproliferative activity against a variety of human cancers .

HY-15141

Staurosporine 85+ Cited Publications Antibiotic AM-2282; STS; AM-2282	Infection Alkaloids Structural Classification Microorganisms Classification of Application Fields Source classification Marine natural products Disease Research Fields Marine microorganism Indole Alkaloids	PKC PKA Apoptosis Bacterial Fungal Antibiotic
Staurosporine is a potent, ATP-competitive and non-selective inhibitor of protein kinases with IC₅₀s of 6 nM, 15 nM, 2 nM, and 3 nM for PKC, PKA, *c-Fgr, and Phosphorylase kinase* respectively. Staurosporine also inhibits TAOK2 with an IC₅₀ of 3 μM. Staurosporine is an apoptosis inducer .

HY-19825

Rebeccamycin	Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Disease Research Anticancer Disease Research Fields Other Antibiotics Cancer	Topoisomerase ADC Cytotoxin Antibiotic
Rebeccamycin, an antitumor antibiotic, inhibits DNA topoisomerase I. Rebeccamycin appears to exert its primary antineoplastic effect by poisoning topoisomerase I and has negligible effect on protein kinase C and topoisomerase II .

HY-N0699

Daphnoretin 1 Publications Verification Dephnoretin; Thymelol	Infection Monophenols Classification of Application Fields Thymelaeaceae Source classification Coumarins Phenols Phenylpropanoids Plants Disease Research Fields Wikstroemia indica	PKC Influenza Virus
Daphnoretin (Dephnoretin), isolated from Wikstroemia indica, possesses antiviral activity . Daphnoretin likes PMA, may direct activation of protein kinase C which in turn activated NADPH oxidase and elicited respiratory burst .

HY-118834

Teleocidin A1 Lyngbyatoxin A	Alkaloids Microorganisms Classification of Application Fields Source classification Disease Research Fields Indole Alkaloids Cancer	PKC
Teleocidin A1 (Lyngbyatoxin A), a highly toxic skin irritant, is a potent activator of protein kinase C (PKC). Teleocidin A1 shows antiproliferative activity against HeLa cancer cells (IC₅₀=9.2 nM) .

HY-12048

Chelerythrine chloride 10+ Cited Publications	Alkaloids Structural Classification Classification of Application Fields Chelidonium majus Source classification Metabolic Disease Plants Isoquinoline Alkaloids Inflammation/Immunology Disease Research Fields Papaveraceae	PKC Bcl-2 Family Apoptosis Autophagy
Chelerythrine chloride is a potent, cell-permeable inhibitor of protein kinase C, with an IC₅₀ of 660 nM. Chelerythrine chloride inhibits the Bcl-XL-Bak BH3 peptide binding with IC₅₀ of 1.5 μM and displaces Bax from Bcl-XL. Chelerythrine chloride induces apoptosis and autophagy.

HY-N2344

Procyanidin A1 1 Publications Verification Proanthocyanidin A1	Flavonoids other families Classification of Application Fields Functional Molecules Source classification Research of Health Products Phenols Polyphenols Plants Biflavones Disease Research Fields Inflammation/Immunology	PKC
Procyanidin A1 (Proanthocyanidin A1) is a procyanidin dimer, which inhibits degranulation downstream of protein kinase C activation or Ca ²⁺ influx from an internal store in RBL-213 cells. Procyanidin A1 has antiallergic effects .

HY-N10866

Phorbol 12-tiglate	Structural Classification Terpenoids Croton tiglium Linn. Source classification Diterpenoids Euphorbiaceae Plants	Others
Phorbol 12-tiglate is a derivative of Phorbol (HY-N2147). Phorbol, a hydrolyzed product of Croton oil, promotes tumor development by activating protein kinase C. Phorbol and its derivatives can be used to construct carcinogenic models in biomedical research .

HY-118442

Sphingosine (d14:1) Tetradecasphing-4-enine	Natural Products Classification of Application Fields Animals Source classification Disease Research Fields Cancer	PKC
Sphingosine (d14:1) (Tetradecasphing-4-enine), a sphingolipid, is a potent Protein kinase C (PKC) inhibitor. Sphingosine (d14:1) prevents its interaction with sn-1,2-diacylglycerol (DAG)/Phorbol esters .

HY-13434

Ionomycin 45+ Cited Publications SQ23377	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Disease Research Anticancer Disease Research Fields Other Antibiotics	Calcium Channel PKC Bacterial Apoptosis Antibiotic
Ionomycin (SQ23377) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin (SQ23377) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin also induces the activation of protein kinase C (PKC) .

HY-18739

Phorbol 12-myristate 13-acetate Maximum Cited Publications 243 Publications Verification PMA; TPA; Phorbol myristate acetate	Ketones, Aldehydes, Acids Croton tiglium Linn. Source classification Euphorbiaceae Plants Inflammation/Immunology Disease Research Fields	PKC SphK NF-κB
Phorbol 12-myristate 13-acetate (PMA), a phorbol ester, is a dual SphK and protein kinase C (PKC) activator . Phorbol 12-myristate 13-acetate is a NF-κB activator. Phorbol 12-myristate 13-acetate induces differentiation in THP-1 cells .

HY-129099

N-Desmethyltamoxifen	Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Disease Research Fields Cancer	PKC Estrogen Receptor/ERR Drug Metabolite Endogenous Metabolite
N-Desmethyltamoxifen is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N-Desmethyltamoxifen is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation .

HY-129099A

N-Desmethyltamoxifen hydrochloride	Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Disease Research Fields Cancer	PKC Estrogen Receptor/ERR Drug Metabolite Endogenous Metabolite
N-Desmethyltamoxifen hydrochloride is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N-Desmethyltamoxifen hydrochloride is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation .

HY-13434A

Ionomycin calcium 45+ Cited Publications SQ23377 calcium	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Disease Research Anticancer Disease Research Fields Other Antibiotics	Calcium Channel PKC Bacterial Apoptosis Antibiotic
Ionomycin calcium (SQ23377 calcium) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin calcium (SQ23377 calcium) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin calcium (SQ23377 calcium) also induces the activation of protein kinase C (PKC) .

HY-126419

Kobophenol A	Infection Classification of Application Fields Source classification Cyperaceae Phenols Polyphenols Plants Disease Research Fields Carex kobomugi Ohwi	SARS-CoV PKC
Kobophenol A, an oligomeric stilbene, blocks the interaction between the ACE2 receptor and S1-RBD with an IC₅₀ of 1.81 μM and inhibits SARS-CoV-2 viral infection in cells with an EC₅₀ of 71.6 μM. Kobophenol A inhibits the activity of partially purified rat brain protein kinase C (PKC) with an IC₅₀ of 52 µM .

HY-N0453R

Hypericin (Standard)	Structural Classification Natural Products Classification of Application Fields Source classification Guttiferae Phenols Hyperlcurn perforatum L. Plants Disease Research Fields Cancer	Apoptosis Influenza Virus Antibiotic Monoamine Oxidase PKC Cytochrome P450 Dopamine β-hydroxylase Reverse Transcriptase Telomerase
Hypericin (Standard) is the analytical standard of Hypericin. This product is intended for research and analytical applications. Hypericin is a naturally occurring substance found in Hyperlcurn perforatum L. Hypericin is an inhibitor of PKC (protein kinase C), MAO (monoaminoxidase), dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP (cytochrome P450). Hypericin shows antitumor, antiviral, antidepressive activities, and can induce apoptosis .

HY-N3634

Corylifol C	Structural Classification Leguminosae Source classification Phenols Polyphenols Psoralea corylifolia L. Plants	Others
Corylifol C is a potent **protein kinase inhibitor with IC₅₀** valueS of 8.7, 3.0, 2.1, 6.4, 4.5, 6.2, 2.3, 1.2, 5.1 μg/ml for ARK5, Aurora-A, Aurora-B, AXL, B-RAF-VE, CDK4/CycD1, TIE2, EGF-R, EPHB4, respectively .

HY-13502

Mitoxantrone 15+ Cited Publications Mitozantrone; NSC 301739	Infection Quinones Structural Classification Classification of Application Fields Anthraquinones Source classification Endogenous metabolite Disease Research Fields Cancer	Topoisomerase PKC Orthopoxvirus Apoptosis Endogenous Metabolite
Mitoxantrone is a potent topoisomerase II inhibitor. Mitoxantrone also inhibits protein kinase C (PKC) activity with an IC₅₀ of 8.5 μM. Mitoxantrone induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone shows antitumor activity . Mitoxantrone also has anti-orthopoxvirus activity with EC₅₀s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively .

HY-13502A

Mitoxantrone dihydrochloride 15+ Cited Publications Mitozantrone dihydrochloride; NSC 301739 dihydrochloride	Infection Quinones Structural Classification Classification of Application Fields Anthraquinones Source classification Endogenous metabolite Disease Research Fields Cancer	Topoisomerase PKC Orthopoxvirus Apoptosis Endogenous Metabolite
Mitoxantrone dihydrochloride is a potent topoisomerase II inhibitor. Mitoxantrone dihydrochloride also inhibits protein kinase C (PKC) activity with an IC₅₀ of 8.5 μM. Mitoxantrone dihydrochloride induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone dihydrochloride shows antitumor activity . Mitoxantrone dihydrochloride also has anti-orthopoxvirus activity with EC₅₀s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively .

HY-16558

Butein 3 Publications Verification 2’,3,4,4’-tetrahydroxy Chalcone	Structural Classification Chalcones Flavonoids other families Classification of Application Fields Anti-aging Source classification Phenols Polyphenols Plants Disease Research Fields Cancer	EGFR Autophagy Apoptosis Phosphodiesterase (PDE)
Butein is a cAMP-specific PDE inhibitor with an IC₅₀ of 10.4 μM for PDE4 . Butein is a specific protein tyrosine kinase inhibitor with IC₅₀s of 16 and 65 μM for EGFR and p60 ^c-src in HepG2 cells . Butein sensitizes HeLa cells to Cisplatin through AKT and ERK/p38 MAPK pathways by targeting FoxO3a . Butein is a SIRT1 activator (STAC).

HY-13502B

Mitoxantrone diacetate Mitozantrone diacetate; NSC 301739 diacetate	Infection Quinones Structural Classification Classification of Application Fields Anthraquinones Source classification Endogenous metabolite Disease Research Fields Cancer	Topoisomerase PKC Orthopoxvirus Apoptosis Endogenous Metabolite
Mitoxantrone diacetate is a potent topoisomerase II inhibitor. Mitoxantrone diacetate also inhibits protein kinase C (PKC) activity with an IC₅₀ of 8.5 μM. Mitoxantrone diacetate induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone diacetate shows antitumor activity . Mitoxantrone diacetate also has anti-orthopoxvirus activity with EC₅₀s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively .

HY-137295

Ingenol 3,20-dibenzoate	Classification of Application Fields Terpenoids Source classification Diterpenoids Euphorbiaceae Euphorbia esula L. Plants Inflammation/Immunology Disease Research Fields	PKC Apoptosis
Ingenol 3,20-dibenzoate is a potent protein kinase C (PKC) isoform-selective agonist. Ingenol 3,20-dibenzoate induces selective translocation of nPKC-delta, -epsilon, and -theta and PKC-mu from the cytosolic fraction to the particulate fraction and induces morphologically typical apoptosis through de novo synthesis of macromolecules. Ingenol 3,20-dibenzoate increases the IFN-γ production and degranulation by NK cells, especially when NK cells are stimulated by NSCLC cells .

HY-121197

Balanol Ophiocordin; Azepinostatin	Structural Classification Natural Products Microorganisms Source classification	PKA PKC
Balanol (Ophiocordin; Azepinostatin) is a potent and ATP competitive PKC/PKA inhibitor against human PKC isozymes α, β-I, β-II, γ, δ, ε, η (IC₅₀s=4-9 nM) and ζ (IC₅₀=150 nM). Balanol also blocks the phosphorylation of *cyclic AMP response element-binding protein* (CREB) and myristoylated alanine-rich C kinase substrate (MARCKS)*. Balanol can be isolated from the fungus Verticillium balanoides* .

HY-N5072

Desmethylglycitein 4',6,7-Trihydroxyisoflavone	Flavonoids Classification of Application Fields Leguminosae Glycine max (L.) merr Source classification Phenols Polyphenols Plants Disease Research Fields Isoflavones Cancer	CDK PI3K PKC
Desmethylglycitein (4',6,7-Trihydroxyisoflavone), a metabolite of daidzein, sourced from Glycine max with antioxidant, and anti-cancer activities. Desmethylglycitein binds directly to CDK1 and CDK2 in vivo, resulting in the suppresses CDK1 and CDK2 activity . Desmethylglycitein is a direct inhibitor of protein kinase C (PKC)α, against solar UV (sUV)-induced matrix matrix metalloproteinase 1 (MMP1) . Desmethylglycitein binds to PI3K in an ATP competitive manner in the cytosol, where it inhibits the activity of PI3K and downstream signaling cascades, leading to the suppression of adipogenesis in 3T3-L1 preadipocytes .

Species:	Human (85) Mouse (8) Rat (1) E.coli (1) Cynomolgus (1)
Tag:	His (54) Tag Free (15) Avi (2) Myc (2) GST (32) MBP (1) Flag (9) Fc (6)
Source:	HEK293 (27) Sf9 insect cells (49) P. pastoris (3) E. coli (17)

Cat. No.	Compare	Product Name	Species	Source

HY-P702648

	PKN1 Protein, Human (sf9, His, Flag) PKN1; Protein kinase N1; PRKCL1, Protein kinase C like 1; serine/threonine-Protein kinase N1; DBK; MGC46204; PAK1; PKN; PRK1; Protein kinase C-like 1; Protein kinase PKN-alpha; Protein kinase C-like PKN; serine-threonine kinase N; protease-activated kinase 1; Protein kinase C-related kinase 1; Protein-kinase C-related kinase 1; serine-threonine Protein kinase N; serine/threonine Protein kinase N; PAK-1; PRKCL1; PKN-ALPHA	Human	Sf9 insect cells

HY-P702642

	PRKCD Protein, Human (sf9, GST) PRKCD; Protein kinase C, delta; Protein kinase C delta type; Protein kinase C delta VIII; tyrosine-Protein kinase PRKCD; MAY1; PKCD; nPKC-delta; MGC49908	Human	Sf9 insect cells

HY-P702649

	PKN2 Protein, Human (sf9, His, GST) PKN2; Protein kinase N2; PRKCL2, Protein kinase C like 2; serine/threonine-Protein kinase N2; cardiolipin activated Protein kinase Pak2; Pak 2; PRK2; PKN gamma; Protein kinase C-like 2; Protein-kinase C-related kinase 2; cardiolipin-activated Protein kinase Pak2; PAK2; Pak-2; PRKCL2; PRO2042; MGC71074; MGC150606	Human	Sf9 insect cells

HY-P702644

PRKCE Protein, Human (sf9, GST)

PRKCE; Protein kinase C, epsilon; Protein kinase C epsilon type; PKCE; nPKC-epsilon; MGC125656; MGC125657
Human Sf9 insect cells

HY-P702639

	PRKCB Protein, Human (sf9, GST) PRKCB; Protein kinase C, beta; PKCB, PRKCB1, PRKCB2, Protein kinase C, beta 1; Protein kinase C beta type; PKC-B; Protein kinase C, beta 1 polypeptide; PKCB; PRKCB1; PRKCB2; PKC-beta; MGC41878	Human	Sf9 insect cells

HY-P702645

	PRKCI Protein, Human (sf9, GST) PRKCI; Protein kinase C, iota; DXS1179E; Protein kinase C iota type; PKCI; PRKC-lambda/iota; aPKC-lambda/iota; atypical Protein kinase C-lambda/iota; nPKC-iota; MGC26534	Human	Sf9 insect cells

HY-P702085

	PRKD1 Protein, Human (Sf9) PRKD1; Serine/threonine-Protein kinase D1; Protein kinase C mu type; Protein kinase D; nPKC-D1; nPKC-mu	Human	Sf9 insect cells
	PRKD1 is a serine/threonine protein kinase that controls multiple cellular functions and transduces transient diacylglycerol (DAG) signals downstream of PKC. PRKD1 Protein, Human (Sf9) is the recombinant human-derived PRKD1 protein, expressed by Sf9 insect cells , with tag free. The total length of PRKD1 Protein, Human (Sf9) is 911 a.a., .

HY-P71184

	PACSIN2 Protein, Human (HEK293, His) Protein kinase C and Casein kinase Substrate in Neurons Protein 2; PACSIN2	Human	HEK293
	The PACSIN2 protein coordinates caveolar morphogenesis and endocytosis to dynamically regulate cell membrane structure. As a lipid-binding protein, PACSIN2 regulates phosphatidic acid-containing membranes. PACSIN2 Protein, Human (HEK293, His) is the recombinant human-derived PACSIN2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PACSIN2 Protein, Human (HEK293, His) is 486 a.a., with molecular weight of ~88.0 kDa.

HY-P702638

	PRKACG Protein, Human (sf9) PRKACG; Protein kinase, cAMP-dependent, catalytic, gamma; cAMP-dependent Protein kinase catalytic subunit gamma; PKACg; PKA C-gamma; serine(threonine) Protein kinase; KAPG	Human	Sf9 insect cells

HY-P702086

	PRKD1 Protein, Human (Sf9, His, GST) PRKD1; Serine/threonine-Protein kinase D1; Protein kinase C mu type; Protein kinase D; nPKC-D1; nPKC-mu	Human	Sf9 insect cells
	PRKD1 is a serine/threonine protein kinase that controls multiple cellular functions and transduces transient diacylglycerol (DAG) signals downstream of PKC. PRKD1 Protein, Human (Sf9, His, GST) is the recombinant human-derived PRKD1 protein, expressed by Sf9 insect cells , with N-8*His, N-GST labeled tag. The total length of PRKD1 Protein, Human (Sf9, His, GST) is 911 a.a., .

HY-P71208

	PKCE Protein, Human (His) Protein kinase C Epsilon Type; nPKC-Epsilon; PRKCE; PKCE	Human	E. coli
	PKCE proteins are calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine protein kinases. PKCE Protein, Human (His) is the recombinant human-derived PKCE protein, expressed by E. coli , with C-6*His labeled tag. The total length of PKCE Protein, Human (His) is 158 a.a., with molecular weight of ~20.0 kDa.

HY-P71183

	PACSIN1 Protein, Human (HEK293, His) Protein kinase C and Casein kinase Substrate in Neurons Protein 1; PACSIN1; KIAA1379	Human	HEK293
	The PACSIN1 protein has multiple functions in cell dynamics, reorganizing microtubules and the actin cytoskeleton. PACSIN1 interacts with MAPT, reduces microtubule stability and inhibits MAPT-induced polymerization. PACSIN1 Protein, Human (HEK293, His) is the recombinant human-derived PACSIN1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PACSIN1 Protein, Human (HEK293, His) is 444 a.a., with molecular weight of ~52.0 kDa.

HY-P702640

PRKCG Protein, Human (sf9, GST)

PRKCG; Protein kinase C, gamma; PKCG, SCA14; Protein kinase C gamma type; MGC57564; PKC gamma; PKCC; PKCG; SCA14; PKC-gamma
Human Sf9 insect cells

HY-P701755

	PRKCZ Protein, Human (Sf9, GST) PRKCZ; Protein kinase C zeta type; nPKC-zeta	Human	Sf9 insect cells
	PKCz proteins are involved in multiple cellular processes, including mitotic signaling, cell proliferation, cell polarity, inflammatory responses, and maintenance of long-term potentiation (LTP). PRKCZ Protein, Human (Sf9, GST) is the recombinant human-derived PKCz protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of PRKCZ Protein, Human (Sf9, GST) is 591 a.a., .

HY-P701966

	PKCi Protein, Human HINT1; Adenosine 5'-monophosphoramidase HINT1; Desumoylating isopeptidase HINT1; Histidine triad nucleotide-binding Protein 1; Protein kinase C inhibitor 1; Protein kinase C-interacting Protein 1; PKCI-1	Human	E. coli
	PKCi protein has adenosine 5'-monophosphate amidase activity and can hydrolyze compounds such as AMP-NH2. It also acts on AMP-morpholidate, GMP-morpholidate, lysyl-AMP, Met-AMP, His-AMP, Asp-AMP, lysyl-GMP and AMP-N-alanine methyl ester. PKCi Protein, Human is the recombinant human-derived PKCi protein, expressed by E. coli , with tag free. The total length of PKCi Protein, Human is 126 a.a., .

HY-P701967

	PKCi Protein, Human (His) HINT1; Adenosine 5'-monophosphoramidase HINT1; Desumoylating isopeptidase HINT1; Histidine triad nucleotide-binding Protein 1; Protein kinase C inhibitor 1; Protein kinase C-interacting Protein 1; PKCI-1	Human	E. coli
	PKCi protein has adenosine 5'-monophosphate amidase activity and can hydrolyze compounds such as AMP-NH2. It also acts on AMP-morpholidate, GMP-morpholidate, lysyl-AMP, Met-AMP, His-AMP, Asp-AMP, lysyl-GMP and AMP-N-alanine methyl ester. PKCi Protein, Human (His) is the recombinant human-derived PKCi protein, expressed by E. coli , with N-6*His labeled tag. The total length of PKCi Protein, Human (His) is 126 a.a., .

HY-P702643

PRKCH Protein, Human (sf9, GST)

PKCL; PKC-L; PRKCL; nPKC-eta; Protein kinase C eta type
Human Sf9 insect cells

HY-P702637

	PRKACB Protein, Human (sf9) PRKACB; Protein kinase, cAMP-dependent, catalytic, beta; cAMP-dependent Protein kinase catalytic subunit beta; PKACb; PKA C-beta; Protein kinase A catalytic subunit beta; cAMP-dependent Protein kinase catalytic beta subunit isoform 4ab; PKACB; MGC9320; MGC41879; DKFZp781I2452	Human	Sf9 insect cells

HY-P75936

	NELL2 Protein, Human (sf9, His) Protein kinase C-binding Protein NELL2; NEL-like Protein 2; NELL2; NRP2	Human	Sf9 insect cells
	NELL2 protein, crucial for neuron survival, modulates MAPK pathways and regulates hypothalamic gonadotropin-releasing hormone (GNRH) secretion, impacting puberty control. NELL2 forms homotrimers and engages with PKC beta-1, indicating intricate molecular interactions in its regulatory functions. NELL2 Protein, Human (sf9, His) is the recombinant human-derived NELL2 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of NELL2 Protein, Human (sf9, His) is 816 a.a., with molecular weight of ~110 kDa.

HY-P702641

PRKCA Protein, Human (sf9, GST)

PRKCA; Protein kinase C alpha; AAG6; PKCA; PRKACA; PKCI+/-; PKCalpha; PKC-alpha
Human Sf9 insect cells

HY-P71850

	KCIP-1 Protein, Mouse (P.pastoris, His) Ywhab; 14-3-3 Protein beta/alpha; Protein kinase C inhibitor Protein 1; KCIP-1	Mouse	P. pastoris
	KCIP-1 protein functions as an adapter for TNFRSF1A/TNFR1, mediating its interaction with FADD. Overexpression induces TNF-induced responses: apoptosis and NF-kappa-B activation. The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A. Stimulation of TNFRSF1A forms plasma membrane-bound complex I, promoting cell survival. Subsequently, KCIP-1 dissociates to form cytoplasmic complex II, inducing apoptosis. KCIP-1 interacts with various proteins in complex I, emphasizing its multifaceted role in cellular processes. KCIP-1 Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived KCIP-1 protein, expressed by P. pastoris, with N-6*His labeled tag. The total length of KCIP-1 Protein, Mouse (P.pastoris, His) is 246 a.a., with molecular weight of ~33 kDa.

HY-P71850Y

	KCIP-1 Protein, Mouse (P.pastoris, His, solution) Ywhab; 14-3-3 Protein beta/alpha; Protein kinase C inhibitor Protein 1; KCIP-1	Mouse	P. pastoris
	KCIP-1 protein serves as the linker of TNFRSF1A/TNFR1 and mediates its interaction with FADD. Overexpression induces TNF-induced responses: apoptosis and NF-κ-B activation. KCIP-1 Protein, Mouse (P.pastoris, His, solution) is the recombinant mouse-derived KCIP-1 protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of KCIP-1 Protein, Mouse (P.pastoris, His, solution) is 246 a.a., with molecular weight of ~33 KDa.

HY-P74630

	PKC iota Protein, Human (sf9, GST) Protein kinase C iota type; PRKC-lambda/iota; nPKC-iota; PRKCI; DXS1179E	Human	Sf9 insect cells
	PKC iota proteins are members of the calcium-dependent cell adhesion protein family and play critical roles in cellular interactions. PKC iota acts through a calcium-dependent mechanism and exhibits a preference for homogeneous interacting, connecting cells. PKC iota Protein, Human (sf9, GST) is the recombinant human-derived PKC iota protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of PKC iota Protein, Human (sf9, GST) is 587 a.a., with molecular weight of ~100 kDa.

HY-P702620

PKC iota Protein, Human (Sf9, His)

Protein kinase C iota type; PRKC-lambda/iota; nPKC-iota; PRKCI; DXS1179E
Human Sf9 insect cells

HY-P71229

	PPP1R14A Protein, Human (His) Protein Phosphatase 1 Regulatory Subunit 14A; 17 kDa PKC-Potentiated Inhibitory Protein of PP1; Protein kinase C-Potentiated Inhibitor Protein of 17 kDa; CPI-17; PPP1R14A; CPI17; PPP1INL	Human	E. coli
	The PPP1R14A protein is a key cellular regulator that effectively inhibits PPP1CA and exhibits significant activity amplification upon phosphorylation. This phosphorylation-induced transformation turns PPP1R14A into a dynamic molecular switch adept at regulating PPP1CA substrate phosphorylation. PPP1R14A Protein, Human (His) is the recombinant human-derived PPP1R14A protein, expressed by E. coli , with C-6*His labeled tag. The total length of PPP1R14A Protein, Human (His) is 147 a.a., with molecular weight of 23-26 kDa.

HY-P75322

	CSK Protein, Mouse (sf9) Tyrosine-Protein kinase CSK; C-Src kinase; CSK	Mouse	Sf9 insect cells
	CSK protein is a non-receptor tyrosine protein kinase that regulates cell growth, differentiation, migration and immune responses by phosphorylating Src family kinases (SFK) (such as LCK, SRC, HCK, FYN, LYN, CSK or YES1) . This phosphorylation induces SFK to form an inactive conformation, thereby inhibiting signaling by receptors such as T cell receptor (TCR) and B cell receptor (BCR). CSK Protein, Mouse (sf9) is the recombinant mouse-derived CSK protein, expressed by Sf9 insect cells , with tag free. The total length of CSK Protein, Mouse (sf9) is 450 a.a., with molecular weight of ~46 kDa.

HY-P72956

	CSK Protein, Human (sf9, GST) Tyrosine-Protein kinase CSK; C-Src kinase; CSK	Human	Sf9 insect cells
	CSK is a non-receptor tyrosine protein kinase that critically regulates cell growth, differentiation, migration and immune responses by phosphorylating tyrosine residues in the C-terminal tail of Src family kinases (SFK). This induces an inactive conformation through intramolecular interactions with the SH2 domain of SFK. CSK Protein, Human (sf9, GST) is the recombinant human-derived CSK protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of CSK Protein, Human (sf9, GST) is 450 a.a., with molecular weight of ~66 kDa.

HY-P72957

	CSK Protein, Mouse (sf9, His-GST) Tyrosine-Protein kinase CSK; C-Src kinase; CSK	Mouse	Sf9 insect cells
	CSK protein is a non-receptor tyrosine protein kinase that regulates cell growth, differentiation, migration and immune responses by phosphorylating Src family kinases (SFK) (such as LCK, SRC, HCK, FYN, LYN, CSK or YES1) . This phosphorylation induces SFK to form an inactive conformation, thereby inhibiting signaling by receptors such as T cell receptor (TCR) and B cell receptor (BCR). CSK Protein, Mouse (sf9, His-GST) is the recombinant mouse-derived CSK protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of CSK Protein, Mouse (sf9, His-GST) is 450 a.a., with molecular weight of ~65 kDa.

HY-P701710

	AURC Protein, Human (Sf9, GST) AURKC; Aurora kinase C; Aurora 3; Aurora/IPL1-related kinase 3; ARK-3; Aurora-related kinase 3; Aurora/IPL1/Eg2 Protein 2; Serine/threonine-Protein kinase 13; Serine/threonine-Protein kinase aurora-C	Human	Sf9 insect cells
	AURC is a key serine/threonine protein kinase that plays a critical regulatory role in mitosis as part of the chromosomal passenger complex (CPC), ensuring accurate chromosome alignment and segregation. It contributes to chromatin-induced microtubule stabilization and spindle assembly. AURC Protein, Human (Sf9, GST) is the recombinant human-derived AURC protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of AURC Protein, Human (Sf9, GST) is 308 a.a., .

HY-P70034

	CDKN2C Protein, Human (His) rHuCyclin-dependent kinase 4 inhibitor C/CDKN2C, His; Cyclin-Dependent kinase 4 Inhibitor C; Cyclin-Dependent kinase 6 Inhibitor; p18-INK4c; p18-INK6; CDKN2C; CDKN6	Human	E. coli
	The CDKN2C protein (also known as p18) interacts strongly with CDK6 and weakly with CDK4. Its functional effects inhibit cell growth and proliferation and are significantly related to the presence of endogenous retinoblastoma protein RB. CDKN2C Protein, Human (His) is the recombinant human-derived CDKN2C protein, expressed by E. coli , with N-6*His labeled tag. The total length of CDKN2C Protein, Human (His) is 168 a.a., with molecular weight of ~17.0 kDa.

HY-P700442

	MERTK Protein, Human (HEK293, His) MERTK; c-mer proto-oncogene tyrosine kinase; tyrosine-Protein kinase Mer; mer; RP38; STK kinase; proto-oncogene c-Mer; MER receptor tyrosine kinase; receptor tyrosine kinase MerTK; MER; c-mer; MGC133349	Human	HEK293
	Mer protein is a receptor tyrosine kinase that transduces signals by binding to ligands such as LGALS3, TUB, TULP1, or GAS6, regulating cell survival, migration, differentiation, and apoptotic cell phagocytosis (endocytosis). Ligand binding induces autophosphorylation of MERTK, creating a docking site for downstream molecules. MERTK Protein, Human (HEK293, His) is the recombinant human-derived MERTK protein, expressed by HEK293 , with C-10*His labeled tag. The total length of MERTK Protein, Human (HEK293, His) is 485 a.a., with molecular weight of 55.4 kDa.

HY-P700446

	MERTK Protein, Mouse (HEK293, His) MERTK; c-mer proto-oncogene tyrosine kinase; tyrosine-Protein kinase Mer; mer; RP38; STK kinase; proto-oncogene c-Mer; MER receptor tyrosine kinase; receptor tyrosine kinase MerTK; MER; c-mer; MGC133349	Mouse	HEK293
	Mer Protein, a receptor tyrosine kinase, transduces signals by binding to ligands like LGALS3, TUB, TULP1, or GAS6. Crucial in processes such as cell survival, migration, differentiation, and apoptotic cell phagocytosis, Mer undergoes autophosphorylation upon ligand binding. This creates binding sites for downstream molecules, leading to interactions with GRB2 or PLCG2 and subsequent phosphorylation of MAPK1, MAPK2, FAK/PTK2, or RAC1. Mer signaling influences macrophage clearance, platelet aggregation, cytoskeleton reorganization, and engulfment. Notably, in the retinal pigment epithelium, Mer regulates phagocytosis of rod outer segment fragments. Additionally, Mer inhibits the innate immune response triggered by Toll-like receptors (TLRs) by activating STAT1, inducing the production of suppressors of cytokine signaling SOCS1 and SOCS3. MERTK Protein, Mouse (HEK293, His) is the recombinant mouse-derived MERTK protein, expressed by HEK293, with C-10*His labeled tag. The total length of MERTK Protein, Mouse (HEK293, His) is 479 a.a., with molecular weight of 55.0 kDa.

HY-P700594

	MERTK Protein, Rat (HEK293, His) MERTK; c-mer proto-oncogene tyrosine kinase; tyrosine-Protein kinase Mer; mer; RP38; STK kinase; proto-oncogene c-Mer; MER receptor tyrosine kinase; receptor tyrosine kinase MerTK; MER; c-mer; MGC133349	Rat	HEK293
	MERTK Protein, a receptor tyrosine kinase, transmits signals by binding to ligands like LGALS3, TUB, TULP1, or GAS6. Governing cell survival, migration, differentiation, and efferocytosis, MERTK undergoes autophosphorylation upon ligand binding. Docking sites for downstream signaling molecules are created, initiating interactions with GRB2 or PLCG2 and phosphorylation of MAPK1, MAPK2, FAK/PTK2, or RAC1. MERTK signaling contributes to diverse processes, including macrophage clearance, platelet aggregation, cytoskeleton reorganization, and engulfment. In the retinal pigment epithelium, MERTK regulates phagocytosis, and it suppresses the innate immune response by activating STAT1 in the Toll-like receptor pathway, promoting the production of SOCS1 and SOCS3. MERTK Protein, Rat (HEK293, His) is the recombinant rat-derived MERTK protein, expressed by HEK293, with N-6*His labeled tag. The total length of MERTK Protein, Rat (HEK293, His) is 479 a.a., with molecular weight of 55.5 kDa.

HY-P701806

	MARK1 Protein, Human MARK1; Serine/threonine-Protein kinase MARK1; MAP/microtubule affinity-regulating kinase 1; PAR1 homolog c; Par-1c; Par1c	Human	E. coli
	MARK1 is an important serine/threonine protein kinase that critically regulates cell polarity and microtubule dynamics. It phosphorylates microtubule-associated proteins (DCX, MAP2, MAP4, MAPT/TAU), causing their dissociation and disassembly. MARK1 Protein, Human is the recombinant human-derived MARK1 protein, expressed by E. coli , with tag free. The total length of MARK1 Protein, Human is 751 a.a., .

HY-P702704

	MERTK Protein, Human (Biotinylated, sf9, Flag) MERTK; c-mer proto-oncogene tyrosine kinase; tyrosine-Protein kinase Mer; mer; RP38; STK kinase; proto-oncogene c-Mer; MER receptor tyrosine kinase; receptor tyrosine kinase MerTK; MER; c-mer; MGC133349	Human	Sf9 insect cells

HY-P701807

	MARK1 Protein, Human (His) MARK1; Serine/threonine-Protein kinase MARK1; MAP/microtubule affinity-regulating kinase 1; PAR1 homolog c; Par-1c; Par1c	Human	E. coli
	MARK1 is an important serine/threonine protein kinase that critically regulates cell polarity and microtubule dynamics. It phosphorylates microtubule-associated proteins (DCX, MAP2, MAP4, MAPT/TAU), causing their dissociation and disassembly. MARK1 Protein, Human (His) is the recombinant human-derived MARK1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of MARK1 Protein, Human (His) is 751 a.a., .

HY-P701641

	TAOK2 Protein, Human (Sf9, GST) TAOK2; Serine/threonine-Protein kinase TAO2; kinase from chicken homolog C; hKFC-C; Prostate-derived sterile 20-like kinase 1; PSK-1; PSK1; Prostate-derived STE20-like kinase 1; Thousand and one amino acid Protein kinase 2	Human	Sf9 insect cells
	TAOK2 is a multifunctional serine/threonine protein kinase that affects membrane blebbing, apoptotic body formation, DNA damage response, and the MAPK14/p38 MAPK cascade. It exhibits broad substrate specificity and can phosphorylate itself, MBP, activated MAPK8, MAP2K3, MAP2K6 and tubulin. TAOK2 Protein, Human (Sf9, GST) is the recombinant human-derived TAOK2 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of TAOK2 Protein, Human (Sf9, GST) is 314 a.a., .

HY-P701642

	TAOK2 Protein, Human (Sf9) TAOK2; Serine/threonine-Protein kinase TAO2; kinase from chicken homolog C; hKFC-C; Prostate-derived sterile 20-like kinase 1; PSK-1; PSK1; Prostate-derived STE20-like kinase 1; Thousand and one amino acid Protein kinase 2	Human	Sf9 insect cells
	TAOK2 is a multifunctional serine/threonine protein kinase that affects membrane blebbing, apoptotic body formation, DNA damage response, and the MAPK14/p38 MAPK cascade. It exhibits broad substrate specificity and can phosphorylate itself, MBP, activated MAPK8, MAP2K3, MAP2K6 and tubulin. TAOK2 Protein, Human (Sf9) is the recombinant human-derived TAOK2 protein, expressed by Sf9 insect cells , with tag free. The total length of TAOK2 Protein, Human (Sf9) is 314 a.a., .

HY-P701790

	JNK3 Protein, Human MAPK10; Mitogen-activated Protein kinase 10; MAP kinase 10; MAPK 10; MAP kinase p49 3F12; Stress-activated Protein kinase 1b; SAPK1b; Stress-activated Protein kinase JNK3; c-Jun N-terminal kinase 3	Human	E. coli
	JNK3 is a critical serine/threonine protein kinase in neuronal processes, regulating proliferation, differentiation, migration, and apoptosis. Activation through MAP2K4/MKK4 and MAP2K7/MKK7 leads to phosphorylation of JNK3, which in turn phosphorylates AP-1 components such as JUN and ATF2, thereby regulating AP-1 transcriptional activity. JNK3 Protein, Human is the recombinant human-derived JNK3 protein, expressed by E. coli , with tag free. The total length of JNK3 Protein, Human is 423 a.a., .

HY-P701791

	JNK3 Protein, Human (His) MAPK10; Mitogen-activated Protein kinase 10; MAP kinase 10; MAPK 10; MAP kinase p49 3F12; Stress-activated Protein kinase 1b; SAPK1b; Stress-activated Protein kinase JNK3; c-Jun N-terminal kinase 3	Human	E. coli
	JNK3 is a critical serine/threonine protein kinase in neuronal processes, regulating proliferation, differentiation, migration, and apoptosis. Activation through MAP2K4/MKK4 and MAP2K7/MKK7 leads to phosphorylation of JNK3, which in turn phosphorylates AP-1 components such as JUN and ATF2, thereby regulating AP-1 transcriptional activity. JNK3 Protein, Human (His) is the recombinant human-derived JNK3 protein, expressed by E. coli , with N-6*His labeled tag. The total length of JNK3 Protein, Human (His) is 423 a.a., .

HY-P701374

	CDK9-CCNK Heterodimer Protein, Human (Sf9) CDK9; CCNK; Cyclin-dependent kinase 9; C-2K; Cell division cycle 2-like Protein kinase 4; Cell division Protein kinase 9; Serine/threonine-Protein kinase PITALRE; Tat-associated kinase complex catalytic subunit; Cyclin-K	Human	Sf9 insect cells
	The CDK9 protein plays a central role in transcriptional regulation, promoting the transition from ineffective to efficient elongation by phosphorylating POLR2A, SUPT5H, and RDBP. As part of the CDK9/cyclin-T complex, it participates in phosphorylation events affecting EP300, MYOD1, RPB1/POLR2A, AR, DSIF, and NELFE. CDK9-CCNK Heterodimer Protein, Human (Sf9) is a recombinant protein dimer complex containing human-derived CDK9-CCNK Heterodimer protein, expressed by Sf9 insect cells , with tag free.

HY-P701375

	CDK9-CCNK Heterodimer Protein, Human (Sf9, GST, FLAG) CDK9; CCNK; Cyclin-dependent kinase 9; C-2K; Cell division cycle 2-like Protein kinase 4; Cell division Protein kinase 9; Serine/threonine-Protein kinase PITALRE; Tat-associated kinase complex catalytic subunit; Cyclin-K	Human	Sf9 insect cells
	The CDK9 protein plays a central role in transcriptional regulation, promoting the transition from ineffective to efficient elongation by phosphorylating POLR2A, SUPT5H, and RDBP. As part of the CDK9/cyclin-T complex, it participates in phosphorylation events affecting EP300, MYOD1, RPB1/POLR2A, AR, DSIF, and NELFE. CDK9-CCNK Heterodimer Protein, Human (Sf9, GST, FLAG) is a recombinant protein dimer complex containing human-derived CDK9-CCNK Heterodimer protein, expressed by Sf9 insect cells , with N-Flag, N-GST labeled tag.

HY-P702689

	CDK9-CCNT1 Protein, Human (sf9, GST, His) CDK9; CCNK; Cyclin-dependent kinase 9; C-2K; Cell division cycle 2-like Protein kinase 4; Cell division Protein kinase 9; Serine/threonine-Protein kinase PITALRE; Tat-associated kinase complex catalytic subunit; Cyclin-K	Human	Sf9 insect cells

HY-P702690

	CDK9-CCNT2 Protein, Human (sf9, GST, Flag, His) CDK9; CCNK; Cyclin-dependent kinase 9; C-2K; Cell division cycle 2-like Protein kinase 4; Cell division Protein kinase 9; Serine/threonine-Protein kinase PITALRE; Tat-associated kinase complex catalytic subunit; Cyclin-K	Human	Sf9 insect cells

HY-P70958

	Mer Protein, Human (HEK293, His) Tyrosine-Protein kinase Mer/Proto-oncogene c-Mer/Receptor tyrosine kinase MerTK/MERTK/MER	Human	HEK293
	MER tyrosine kinase (MERTK) is a transmembrane protein with transmembrane receptor protein tyrosine kinase activity. MERTK has oncogenic properties and is often overexpressed or activated in various malignancies, activating several downstream signaling pathways including MAPK/ERK, PI3K/AKT, and JAK/STAT. MERTK is involved in animal organ development, synapse elimination, neutrophil clearance and protein kinase B signaling. Mer Protein, Human (HEK293, His) is the recombinant human-derived Mer protein, expressed by HEK293, with C-6*His labeled tag. The total length of Mer Protein, Human (HEK293, His) is 323 a.a., with molecular weight of 60-120 kDa.

HY-P701798

	MAP2K7 Protein, Human (Sf9) MAP2K7; Dual specificity mitogen-activated Protein kinase kinase 7; MAP kinase kinase 7; MAPKK 7; JNK-activating kinase 2; MAPK/ERK kinase 7; MEK 7; Stress-activated Protein kinase kinase 4; SAPK kinase 4; SAPKK-4; SAPKK4; c-Jun N-terminal kinase kinase 2; JNK kinase 2; JNKK 2	Human	Sf9 insect cells
	MAP2K7 protein is a dual-specificity kinase involved in the MAP kinase signal transduction pathway. MAP2K7 Protein, Human (Sf9) is the recombinant human-derived MAP2K7 protein, expressed by Sf9 insect cells , with tag free. The total length of MAP2K7 Protein, Human (Sf9) is 418 a.a., .

HY-P701377

	CDK9-CCNT2 Heterodimer Protein, Human (Sf9) CDK9; CCNT2; Cyclin-dependent kinase 9; C-2K; Cell division cycle 2-like Protein kinase 4; Cell division Protein kinase 9; Serine/threonine-Protein kinase PITALRE; Tat-associated kinase complex catalytic subunit; Cyclin-T2; CycT2	Human	Sf9 insect cells
	The CDK9 protein plays a central role in transcriptional regulation, promoting the transition from ineffective to efficient elongation by phosphorylating POLR2A, SUPT5H, and RDBP. As part of the CDK9/cyclin-T complex, it participates in phosphorylation events affecting EP300, MYOD1, RPB1/POLR2A, AR, DSIF, and NELFE. CDK9-CCNT2 Heterodimer Protein, Human (Sf9) is a recombinant protein dimer complex containing human-derived CDK9-CCNT2 Heterodimer protein, expressed by Sf9 insect cells , with tag free.

HY-P701799

	MAP2K7 Protein, Human (Sf9, His, GST) MAP2K7; Dual specificity mitogen-activated Protein kinase kinase 7; MAP kinase kinase 7; MAPKK 7; JNK-activating kinase 2; MAPK/ERK kinase 7; MEK 7; Stress-activated Protein kinase kinase 4; SAPK kinase 4; SAPKK-4; SAPKK4; c-Jun N-terminal kinase kinase 2; JNK kinase 2; JNKK 2	Human	Sf9 insect cells
	MAP2K7 protein is a dual-specificity kinase involved in the MAP kinase signal transduction pathway. MAP2K7 Protein, Human (Sf9, His, GST) is the recombinant human-derived MAP2K7 protein, expressed by Sf9 insect cells , with N-8*His, N-GST labeled tag. The total length of MAP2K7 Protein, Human (Sf9, His, GST) is 418 a.a., .

HY-P701376

	CDK9-CCNT1 Heterodimer Protein, Human (Sf9) CDK9; CCNT1; Cyclin-dependent kinase 9; C-2K; Cell division cycle 2-like Protein kinase 4; Cell division Protein kinase 9; Serine/threonine-Protein kinase PITALRE; Tat-associated kinase complex catalytic subunit; Cyclin-T1; CycT1; Cyclin-T	Human	Sf9 insect cells
	The CDK9 protein plays a central role in transcriptional regulation, promoting the transition from ineffective to efficient elongation by phosphorylating POLR2A, SUPT5H, and RDBP. As part of the CDK9/cyclin-T complex, it participates in phosphorylation events affecting EP300, MYOD1, RPB1/POLR2A, AR, DSIF, and NELFE. CDK9-CCNT1 Heterodimer Protein, Human (Sf9) is a recombinant protein dimer complex containing human-derived CDK9-CCNT1 Heterodimer protein, expressed by Sf9 insect cells , with tag free.

HY-P71475

	*Propionate kinase/TdcD Protein, E.coli (Myc, His)* tdcD; c3873; Propionate kinase; EC 2.7.2.15	E.coli	E. coli
	Propionate kinase, also known as TdcD protein, plays a key role in cellular metabolism by catalyzing the conversion of propionyl phosphate and ADP into propionate and ATP. This enzymatic process is an integral part of the metabolic pathways associated with propionate utilization, facilitating the conversion of propionyl phosphate into propionate, a compound essential for various cellular functions. Propionate kinase/TdcD Protein, E.coli (Myc, His) is the recombinant E. coli-derived Propionate kinase/TdcD protein, expressed by E. coli , with N-His, C-Myc labeled tag. The total length of Propionate kinase/TdcD Protein, E.coli (Myc, His) is 402 a.a., with molecular weight of ~50.4 kDa.

Cat. No.	Product Name	Chemical Structure

HY-10230S

Midostaurin-d5
Midostaurin-d₅ is a deuterium labeled Midostaurin. Midostaurin is a multi-targeted protein kinase inhibitor which inhibits PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ and VEGFR1/2 with IC50s ranging from 22-500 nM[1].

HY-15463S2

Imatinib-d3 hydrochloride

Imatinib-d₃ (hydrochloride) is the deuterium labeled Imatinib. Imatinib (STI571) is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity. Imatinib (STI571) works by binding close to the ATP binding site, locking it in a closed or self-inhibited conformation, therefore inhibiting the enzyme activity of the protein semicompetitively. Imatinib also is an inhibitor of SARS-CoV and MERS-CoV.

HY-101047S

D-erythro-Sphingosine-d7
D-erythro-Sphingosine-d₇ is the deuterium labeled D-erythro-Sphingosine. D-erythro-Sphingosine (Erythrosphingosine) is a very potent activator of p32-kinase with an EC50 of 8 μM, and inhibits protein kinase C (PKC). D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator[1][2][3][4].

HY-13502S

Mitoxantrone-d8
Mitoxantrone-d₈ (mitozantrone-d8) is the deuterium labeled Mitoxantrone. Mitoxantrone is a topoisomerase II inhibitor and also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 μM[1][2].

Cat. No.	Product Name	Application	Reactivity

HY-P83145

PKN2 Antibody (YA2890) PKN2; PRK2; PRKCL2; Serine/threonine-Protein kinase N2; PKN gamma; Protein kinase C-like 2; Protein-kinase C-related kinase 2	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat

HY-P82883

Phospho-PKC delta (Ser299) Antibody (YA2628)

Protein kinase C delta type; Tyrosine-Protein kinase PRKCD; nPKC-delta
WB, IHC-P, IP Human

HY-P81127

PKA alpha + beta Antibody PRKACA/PRKACB; PRKACA + PRKACB; PKA alpha + beta; PKA alpha; PKA beta; cAMP dependent Protein kinase alpha catalytic subunit; cAMP dependent Protein kinase beta catalytic subunit; cAMP dependent Protein kinase catalytic subunit alpha; cAMP dependent Protein kinase catalytic subunit beta; DKFZp781I2452; MGC102831; MGC41879; MGC48865; MGC9320; PKA C alpha; PKA C beta; PKACA; PKACB; PRKACA; PRKACB; Protein kinase A catalytic subunit alpha; Protein kinase A catalytic subunit; Protein kinase A catalytic subunit beta; Protein kinase cAMP dependent catalytic alpha; Protein kinase cAMP dependent catalytic beta; cAMP dependent Protein kinase catalytic subunit alpha isoform 1; cAMP-dependent Protein kinase catalytic subunit alpha; KAPCA_HUMAN; KAPCB_HUMAN; PKA C alpha; PKA C-alpha; PKACA; PRKACA; Protein kinase A catalytic subunit; Protein kinase cAMP dependent catalytic alpha.	WB; ELISA; IHC-P; IHC-F; ICC; IF	Human, Mouse(predicted: Rat)
PKA alpha + beta Antibody is an unconjugated, approximately 40 kDa, rabbit-derived, anti-PKA alpha + beta polyclonal antibody. PKA alpha + beta Antibody can be used for: WB, ELISA, IHC-P, IHC-F, ICC, IF expriments in human, mouse, and predicted: rat background without labeling.

HY-P81914

PKD1 Antibody (YA1659)

PRKD1; PKD; PKD1; PRKCM; Serine/threonine-Protein kinase D1; Protein kinase C mu type; Protein kinase D; nPKC-D1; nPKC-mu
WB Human, Rat
HY-P81361

PRKCQ Antibody (YA1106)

PRKCT; PRKCQ; nPKC-theta; Protein kinase C theta type
IHC-P Human

HY-P83238

HINT1 Antibody (YA2983) HINT1; HINT; PKCI1; PRKCNH1; Histidine triad nucleotide-binding Protein 1; Adenosine 5'-monophosphoramidase; Protein kinase C inhibitor 1; Protein kinase C-interacting Protein 1; PKCI-1	WB, ICC/IF, IP	Human

HY-P83417

PKC theta Antibody (YA3162)

PRKCQ; PRKCT; Protein kinase C theta type; nPKC-theta
WB Human, Rat
HY-P82923

14-3-3 gamma Antibody (YA2668)

YWHAG; 14-3-3 Protein gamma; Protein kinase C inhibitor Protein 1; KCIP-1
WB Human, Mouse, Rat
HY-P82204

41701 Antibody (YA1949)

YWHAB; 14-3-3 Protein beta/alpha; Protein 1054; Protein kinase C inhibitor Protein 1; KCIP-1
WB Human, Rat

HY-P80869

PKC eta Antibody nPKC eta; PKC h; PKC L; PKCh; PKCL; Prkch; PRKCL; Protein kinase C eta	WB, IP	Human, Mouse, Rat
PKC eta Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 78 kDa, targeting to PKC eta. It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat.

HY-P82934

Phospho-PKC zeta (Thr560) Antibody (YA2679)

PRKCZ; PKC2; Protein kinase C zeta type; nPKC-zeta
WB, IHC-P Human, Mouse, Rat
HY-P81649

Phospho-PKC (Ser660) Antibody (YA1394)

PRKCA; PKCA; PRKACA; Protein kinase C alpha type; PKC-A; PKC-alpha
WB, IHC-P Human, Rat
HY-P81298

Phospho-PKC alpha (Ser657) Antibody (YA1023)

PRKCA; PKCA; PRKACA; Protein kinase C alpha type; PKC-A; PKC-alpha
WB, IHC-P Human, Mouse, Rat
HY-P81298A

Phospho-PKC alpha (Thr638) Antibody (YA1024)

PRKCA; PKCA; PRKACA; Protein kinase C alpha type; PKC-A; PKC-alpha
WB, IHC-P, IP Human, Mouse, Rat
HY-P82886

Phospho-PKC zeta/lambda (Thr410/Thr412) Antibody (YA2631)

PRKCG; PKCG; Protein kinase C gamma type; PKC-gamma
WB, IHC-P Human, Mouse
HY-P82884

14-3-3 epsilon Antibody (YA2629)

14-3-3 epsilon; 14-3-3E; 143E; KCIP-1; MDCR; Protein kinase C inhibitor Protein-1; YWHAE
WB, IHC-P, ICC/IF, FC Human, Mouse, Rat
HY-P82997

CSK Antibody (YA2742)

CSK; Tyrosine-Protein kinase CSK; C-Src kinase; Protein-tyrosine kinase CYL
WB, IHC-P Human, Mouse, Rat

HY-P80887

RSK3 Antibody RPS6KA2; MAPKAPK1C; RSK3; Ribosomal Protein S6 kinase alpha-2; S6K-alpha-2; 90 kDa ribosomal Protein S6 kinase 2; p90-RSK 2; p90RSK2; MAP kinase-activated Protein kinase 1c; MAPK-activated Protein kinase 1c; MAPKAP kinase 1c; MAPKAPK-1c; Ri	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Hamster
RSK3 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 83 kDa, targeting to RSK3. It can be used for WB,IHC-F,IHC-P,ICC/IF,IP assays with tag free, in the background of Human, Hamster.

HY-P82405

MARK3 Antibody (YA2150) MARK3; CTAK1; EMK2; MAP/microtubule affinity-regulating kinase 3; C-TAK1; cTAK1; Cdc25C-associated Protein kinase 1; ELKL motif kinase 2; EMK-2; Protein kinase STK10; Ser/Thr Protein kinase PAR-1; Par-1a; Serine/threonine-Protein kinase p78	WB, ICC/IF, IP, FC	Mouse, Human

HY-P80743

Lck Antibody (YA712) LCK; Tyrosine-Protein kinase Lck; Leukocyte C-terminal Src kinase; LSK; Lymphocyte cell-specific Protein-tyrosine kinase; Protein YT16; Proto-oncogene Lck; T cell-specific Protein-tyrosine kinase; p56-LCK	WB	Human
Lck Antibody (YA712) is a non-conjugated and Mouse origined monoclonal antibody about 58 kDa, targeting to Lck (3E5). It can be used for WB assays with tag free, in the background of Human.

HY-P80728

JNK Antibody AI849689; c Jun N terminal kinase 1; C-JUN kinase 1; c-Jun N-terminal kinase 1; EC 2.7.11.24; JAK 1A; JAK1A; JNK 1; JNK 46; JNK; JNK-46; JNK1A2; JNK21B1/2; MAP kinase 8; MAPK 8; MAPK8; Mitogen activated Protein kinase 8; Mitogen-activated Protein kinase 8	WB, IP	Human, Mouse, Rat, Hamster
JNK Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 48 kDa, targeting to JNK. It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat, Hamster.

HY-P83221

MERTK Antibody (YA2966)

MERTK; MER; Tyrosine-Protein kinase Mer; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK
WB, IHC-P, IP Human
HY-P82610

ULK3 Antibody (YA2355)

Serine/threonine-Protein kinase ULK3; Ulk3; unc 51 like kinase 3 (C. elegans); Unc-51-like kinase 3
WB Human

HY-P80729

JNK1 Antibody (YA720) AI849689; c Jun N terminal kinase 1; C-JUN kinase 1; c-Jun N-terminal kinase 1; EC 2.7.11.24; JAK 1A; JAK1A; JNK 1; JNK 46; JNK; JNK-46; JNK1A2; JNK21B1/2; MAP kinase 8; MAPK 8; MAPK8; Mitogen activated Protein kinase 8; Mitogen-activated Protein kinase 8	WB, ICC/IF	Human, Mouse, Rat
JNK1 (1A4) Antibody is a non-conjugated and Mouse origined monoclonal antibody about 48 kDa, targeting to JNK1 (1A4). It can be used for WB,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

HY-P80789

Phospho-AKT (Thr308) Antibody AKT1; PKB; RAC; RAC-alpha serine/threonine-Protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha	ICC/IF, WB, IHC-F, IHC-P, ELISA	Human, Mouse, Rat
Phospho-AKT (Thr308) Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 56 kDa, targeting to Phospho-AKT (Thr308). It can be used for ICC/IF,WB,IHC-F,IHC-P,ELISA assays with tag free, in the background of Human, Mouse, Rat.

HY-P80788

Phospho-AKT1 (Ser473) Antibody AKT1; PKB; RAC; RAC-alpha serine/threonine-Protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha	WB	Human, Mouse, Rat
Phospho-AKT1 (Ser473) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 56 kDa, targeting to Phospho-AKT (Ser473). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

HY-P80831

Phospho-JNK1 (Thr183/Tyr185) Antibody AI849689; c Jun N terminal kinase 1; C-JUN kinase 1; c-Jun N-terminal kinase 1; EC 2.7.11.24; JAK 1A; JAK1A; JNK 1; JNK 46; JNK; JNK-46; JNK1A2; JNK21B1/2; MAP kinase 8; MAPK 8; MAPK8; Mitogen activated Protein kinase 8; Mitogen-activated Protein kinase 8	WB, IP	Human, Rat
Phospho-JNK1 (Thr183/Tyr185) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 48 kDa, targeting to Phospho-JNK1 (Thr183/Tyr185). It can be used for WB,IP assays with tag free, in the background of Human, Rat.

HY-P81981

PKA C gamma Antibody (YA1726)

PRKACG; cAMP-dependent Protein kinase catalytic subunit gamma; PKA C-gamma
WB, IP Human, Mouse, Rat

HY-P80681

FYN Antibody FYN; Tyrosine-Protein kinase Fyn; Proto-oncogene Syn; Proto-oncogene c-Fyn; Src-like kinase; SLK; p59-Fyn	WB	Human, Mouse, Rat
FYN Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 61 kDa, targeting to FYN. It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

HY-P81638

Neurogranin Antibody (YA1383)

neurogranin (Protein kinase C substrate; RC3); RC3; hng
WB, IHC-F, IHC-P, ICC/IF, IP Human, Mouse, Rat

HY-P80659

ErbB 3 Antibody ERBB3; HER3; Receptor tyrosine-Protein kinase erbB-3; Proto-oncogene-like Protein c-ErbB-3; Tyrosine kinase-type cell surface receptor HER3	WB	Human
ErbB 3 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 148 kDa, targeting to ErbB 3. It can be used for WB assays with tag free, in the background of Human.

HY-P83223

NME2 Antibody (YA2968) NME2; NM23B; Nucleoside diphosphate kinase B; NDK B; NDP kinase B; C-myc purine-binding transcription factor PUF; Histidine Protein kinase NDKB; nm23-H2	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat

HY-P82152

Yes1 Antibody (YA1897)

YES1; YES; Tyrosine-Protein kinase Yes; Proto-oncogene c-Yes; p61-Yes
WB, IHC-P, ICC/IF, IP Human, Mouse, Rat

HY-P80660

ErbB 4 Antibody ERBB4; HER4; Receptor tyrosine-Protein kinase erbB-4; Proto-oncogene-like Protein c-ErbB-4; Tyrosine kinase-type cell surface receptor HER4; p180erbB4	WB	Human, Rat
ErbB 4 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 147 kDa, targeting to ErbB 4. It can be used for WB assays with tag free, in the background of Human, Rat.

HY-P80880

Raf1 Antibody RAF1; RAF; RAF proto-oncogene serine/threonine-Protein kinase; Proto-oncogene c-RAF; cRaf; Raf-1	WB, ICC/IF	Human, Mouse, Rat
Raf1 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 73 kDa, targeting to Raf1. It can be used for WB,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

HY-P82911

Phospho-Src (Tyr530) Antibody (YA2656)

SRC; SRC1; Proto-oncogene tyrosine-Protein kinase Src; Proto-oncogene c-Src; pp60c-src; p60-Src
WB, IP Rat

HY-P80803

Phospho-c-Met (Tyr1349) Antibody MET; Hepatocyte growth factor receptor; HGF receptor; HGF/SF receptor; Proto-oncogene c-Met; Scatter factor receptor; SF receptor; Tyrosine-Protein kinase Met	WB, IP	Human
Phospho-c-Met (Tyr1349) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 156 kDa, targeting to Phospho-c-Met (Tyr1349). It can be used for WB,IP assays with tag free, in the background of Human.

HY-P80276

Phospho-AKT1(Ser473) Antibody AKT 1 antibody; AKT antibody; AKT1 antibody; AKT1_HUMAN antibody; MGC99656 antibody; PKB antibody; PKB-ALPHA antibody; PRKBA antibody; Protein kinase B Alpha antibody; Protein kinase B antibody; Proto-oncogene c-Akt antibody; RAC Alpha antibody; RAC antibody; RAC-alpha serine/threonine-Protein kinase antibody; RAC-PK-alpha antibody;	WB, ICC/IF, IHC-P	Human, Mouse
Phospho-Akt1(Ser473) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 56 kDa, targeting to Phospho-Akt1(Ser473). It can be used for WB,ICC/IF,IHC-P assays with tag free, in the background of Human, Mouse.

HY-P80648

EGFR Antibody (YA775) EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-Protein kinase erbB-1	WB, ICC/IF, IP	Human, Monkey
EGFR Antibody (YA775) is a non-conjugated and Mouse origined monoclonal antibody about 134 kDa, targeting to EGFR (6H11). It can be used for WB,ICC/IF,IP assays with tag free, in the background of Human, Monkey.

HY-P80619

c-Kit Antibody KIT; SCFR; Mast/stem cell growth factor receptor Kit; SCFR; Piebald trait Protein; PBT; Proto-oncogene c-Kit; Tyrosine-Protein kinase Kit; p145 c-kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD antigen CD117	WB, IHC-F, IHC-P, ICC/IF, ELISA	Human, Mouse, Rat, Monkey
c-Kit Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 110 kDa, targeting to c-Kit. It can be used for WB,IHC-F,IHC-P,ICC/IF,ELISA assays with tag free, in the background of Human, Mouse, Rat, Monkey.

HY-P80808

Phospho-EGFR (Tyr1068) Antibody EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-Protein kinase erbB-1	WB, IHC-F, IHC-P, ICC/IF	Human
Phospho-EGFR (Tyr1068) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 134 kDa, targeting to Phospho-EGFR (Tyr1068). It can be used for WB,IHC-F,IHC-P,ICC/IF assays with tag free, in the background of Human.

HY-P80809

Phospho-EGFR (Tyr1092) Antibody EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-Protein kinase erbB-1	WB, IHC-P	Human, Mouse, Rat
Phospho-EGFR (Tyr1092) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 134 kDa, targeting to Phospho-EGFR (Tyr1092). It can be used for WB,IHC-P assays with tag free, in the background of Human, Mouse, Rat.

HY-P80810

Phospho-EGFR (Tyr1173) Antibody EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-Protein kinase erbB-1	WB, IHC-F, IHC-P, ICC/IF, IP	Human
Phospho-EGFR (Tyr1173) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 134 kDa, targeting to Phospho-EGFR (Tyr1173). It can be used for WB,IHC-F,IHC-P,ICC/IF,IP assays with tag free, in the background of Human.

HY-P82872

HspB8 Antibody (YA2617) HSPB8; CRYAC; E2IG1; HSP22; PP1629; Heat shock Protein beta-8; HspB8; Alpha-crystallin C chain; E2-induced gene 1 Protein; Protein kinase H11; Small stress Protein-like Protein HSP22	WB, IHC-P, ICC/IF	Human, Mouse, Rat

HY-P80658

HER2 Antibody (YA771) ERBB2; HER2; MLN19; NEU; NGL; Receptor tyrosine-Protein kinase erbB-2; Metastatic lymph node gene 19 Protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; CD antigen CD340	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
ErbB 2 Antibody (YA771) is a non-conjugated and Mouse origined monoclonal antibody about 138 kDa, targeting to ErbB 2 (1C4). It can be used for WB,IHC-F,IHC-P,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

HY-P80008

AKT1 Antibody (YA634) AKT 1; AKT; AKT1; AKT1_HUMAN ; MGC99656; PKB; PKB-ALPHA; PRKBA; Protein kinase B Alpha ; Proto-oncogene c-Akt; RAC Alpha;	WB, IHC-P, IP, FC	Human, Mouse
AKT1 Antibody (YA634) is a non-conjugated and Rabbit origined monoclonal antibody about 56 kDa, targeting to AKT1. It can be used for WB,IHC-P,IP,FC assays with tag free, in the background of Human, Mouse.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks